| abstract |
A fusion protein comprising a functional IL-6 molecule and a functional DS-sIL-6R molecule, wherein the protein increases the expression of one or more of MIP-1á, MIP-1â, RANTES and IP-10; an expression vector and host cell comprising said fusion protein; and a pharmaceutical composition comprising said fusion protein and the use of the protein in the manufacture of a medicament for the prophylaxis or treatment of an infectious disease, such as HIV, an inflammatory disorder, such as bacterial peritonitis, or an immunological disorder, such as rheumatoid arthritis. |