abstract |
A chimeric immunomodulatory compound (CIC) comprising two or more nucleic acid moieties and one or more non-nucleic acid spacer moieties, wherein at least one non-nucleic acid spacer moiety is covalently joined to two nucleic acid moieties, wherein said spacer is not a polypeptide, wherein at least one nucleic acid moiety comprises the sequence 5'-CG-3' and wherein said CIC has immunomodulatory activity. |