abstract |
Disclosed is a compound of the formula (I), wherein A is selected from the group consisting of compounds such as (a), (b) and (c); and B is the compound of formula (II). The use of the compound is described to be for the manufacture of a medicament for treating a chemokine-mediated disease wherein the chemokine binds to a CXCR2 and/or CXCR1 receptor in a mammal. the chemokine mediated disease is selected from conditions such as acne, asthma, arthritis and inflammatory bowel disease. |