http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-529238-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20d02d0dfff5297bb57ce202191a00cc |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 |
| filingDate | 2003-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_690a74fd80f4790ea39f73ee57939533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8237399f607922963b2d34ece9f5e5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bb1014b3c44b52685c82f3c725d9211 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_929003f8a9e83a0e16b445f3f01301b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ff4944081c9bb82e1f6ad7b4cb77a4b |
| publicationDate | 2005-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-529238-A |
| titleOfInvention | Methods of producing and screening mutants of a Mycobacterium species of the M. tuberculosis complex for attenuation |
| abstract | Methods of screening for attenuated strains of Mycobacterium tuberculosis complex, which comprise at least one inactive gene, are described. The screening comprises steps of isolating a Mycobacterium species to be screened, growing the isolated mutants for 5-10 weeks in a complete medium, transferring the mutants to minimal media and selecting the mutants based on their inability to grow in minimal media. The figure shows a Southern blot hybridization after EcoR1 digestion and probing with neo of eight recombinants that were unable to grow in a minimal medium (lanes 1-5 and 7-9) and one recombinant that failed the screen and grew in the minimal medium (lane 6). (62) Divided out of 519395 |
| priorityDate | 2003-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.