http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-529187-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf82b2c04febd9f5fc6ead8595272b9a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 |
filingDate | 2002-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_230b08160c80fe23de9be8b04e01cc8e |
publicationDate | 2005-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NZ-529187-A |
titleOfInvention | Composition for treating drug-induced constipation with 15-keto-prostaglandins |
abstract | Disclosed is the use of a 15-keto compound represented by the formula (II): wherein L and M are hydrogen, hydroxy, halogen, lower alkyl, hydroxy(lower)alkyl or oxo, wherein at least one of L and M is a group other than hydrogen, and the five-membered ring may have at least one double bond; A is -COCH2OH, -COOH or a functional derivative thereof; B is -CH2-CH2-, -CH=CH-, -CC-; X1 and X2 are H, (lower) alkyl, or halogen provided that at least one of X1 and X2 is halogen; R1 is a saturated or unsaturated bivalent lower or medium aliphatic hydrocarbon residue, which is unsubstituted or substituted with halogen, alkyl, hydroxy, oxo, aryl or heterocyclic group and at least one of carbon atom in the aliphatic hydrocarbon is optionally substituted by oxygen, nitrogen or sulfur; R2 is a single bond or lower alkylene; and R3 is lower alkyl, lower alkoxy, cyclo(lower)alkyl, cyclo(lower)alky aryl, aryloxy, heterocyclic group or heterocyclic-oxy group, for manufacturing a pharmaceutical composition for treating drug-induced constipation. |
priorityDate | 2001-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 184.