http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-529187-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf82b2c04febd9f5fc6ead8595272b9a
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-557
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5575
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-10
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557
filingDate 2002-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_230b08160c80fe23de9be8b04e01cc8e
publicationDate 2005-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-529187-A
titleOfInvention Composition for treating drug-induced constipation with 15-keto-prostaglandins
abstract Disclosed is the use of a 15-keto compound represented by the formula (II): wherein L and M are hydrogen, hydroxy, halogen, lower alkyl, hydroxy(lower)alkyl or oxo, wherein at least one of L and M is a group other than hydrogen, and the five-membered ring may have at least one double bond; A is -COCH2OH, -COOH or a functional derivative thereof; B is -CH2-CH2-, -CH=CH-, -CC-; X1 and X2 are H, (lower) alkyl, or halogen provided that at least one of X1 and X2 is halogen; R1 is a saturated or unsaturated bivalent lower or medium aliphatic hydrocarbon residue, which is unsubstituted or substituted with halogen, alkyl, hydroxy, oxo, aryl or heterocyclic group and at least one of carbon atom in the aliphatic hydrocarbon is optionally substituted by oxygen, nitrogen or sulfur; R2 is a single bond or lower alkylene; and R3 is lower alkyl, lower alkoxy, cyclo(lower)alkyl, cyclo(lower)alky aryl, aryloxy, heterocyclic group or heterocyclic-oxy group, for manufacturing a pharmaceutical composition for treating drug-induced constipation.
priorityDate 2001-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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