| abstract |
A stable pharmaceutical composition suitable for oral administration comprises an effective amount of pravastatin and a carrier. The carrier comprises at least one water soluble diluent selected from compressible sugar, lactose, sucrose, sorbitol, mannitol, dextrates, dextrin, dextrose, maltodextrin and mixtures thereof or a water dispersible diluent selected from cellulose, cellulosic derivatives, starch, starch derivatives, clay, clay minerals and mixtures thereof, and sodium stearyl fumarate as a lubricant to impart a pH between 6.5 and 8.5 to an aqueous dispersion of the composition. Also described is a process for making the composition. |