http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-528350-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b87a9240552d4631cc03131a7d23547f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02 |
| filingDate | 1998-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e87fc6e5525a7b559a3b5d107745c66f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56da479bf76deff4a16338cf96ecb781 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12869d0e6a21aefd96226b674e3b2132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f5b1d1132ad3ceb402d79c22d61e1f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dd8807c80cf16f9e851c504da41487f |
| publicationDate | 2005-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-528350-A |
| titleOfInvention | A vaccine-induced hepatitis B viral strain and uses thereof |
| abstract | Disclosed is a method of obtaining antibodies to a polypeptide which is a mutant major surface antigen of a strain of hepatitis B virus, which differ from the amino acid sequence of a major surface antigen of a wildtype hepatitis B virus in that the amino acid at position number 145 of such polypeptide is an arginine, rather than a glycine, and not to the major surface antigen of a wildtype hepatitis B virus, comprising: (a) obtaining the polypeptide in a purified form; (b) immunizing a nonùhuman organism capable of producing antibodies against the purified polypeptide; (c) collecting the produced antibodies; (d) combining the produced antibodies and the purified polypeptide under conditions to form a complex; and (e) determining which produced antibodies form a complex with the purified polypeptide so as to obtain antibodies to the polypeptide. Such polypeptides are useful for determining whether a subject is infected with a strain of hepatitis B virus designated Human Hepatitis B Virus Surface Antigen-æSÆ-145 Singapore strain (glycine to arginine). (62) Divided out of 508892 |
| priorityDate | 1998-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.