| abstract |
Compounds of the formula (I) that are useful as metalloproteinase inhibitors, especially as inhibitors of MMP12 are disclosed, wherein X is NR1, O or S; Y1 and Y2 are independently selected from O and S; Z is NR2, O or S; m is 0 or 1; R5 is a bicyclic or tricyclic group as defined in the specification; and wherein R1, R2, R3, R4, R6 and A are as defined in the specification. |