abstract |
Disclosed are acylated 6,7,8,9-tetrahydro-5H-benzocycloheptenyl amine compounds of formula (I), wherein: A is CH2, CHOH or CH-(C1-3alkyl), B, C and D are independently CH2 or CH-(C1-3alkyl), and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the stimulation of the expression of endothelial NO-synthase. |