abstract |
Quinazoline derivatives of formula (I) and the production thereof, wherein Ra, Rb and Rc are as defined in the specification, their tautomers, their stereoisomers and their salts, especially their physiologically acceptable salts with inorganic or organic acids are disclosed. These compounds have valuable pharmacological properties, especially an inhibiting effect upon signal transduction caused by tyrosine kinase, which makes them suitable for use in the treatment of diseases, especially of tumoral diseases, diseases of the lung and the respiratory tract. |