http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-526175-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6028fbdca2aa7d64e81e43267befa26 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55544 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate | 2001-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc1b4c32e890af1219cc863847ac899 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f05ca42edd2988b097b33b9b7bf5545a |
| publicationDate | 2006-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-526175-A |
| titleOfInvention | Nucleic acid adjuvants |
| abstract | An adjuvant composition comprising first and second nucleic acid sequences is described to enhance an immune response against an antigen. The first nucleic acid sequence is a truncated A subunit coding region obtained or derived from a bacterial ADP-ribosylating exotoxin. The second nucleic acid sequence is a truncated B subunit coding region obtained or derived from a bacterial ADP-ribosylating exotoxin. The first and second nucleic acid sequences are operably linked to, or are each operably linked to, a promoter active in a mammalian cell. Use of the first and second nucleic acid is disclosed to be for the manufacture of a medicament for enhancing an immune response in a vertebrate subject against an antigen of interest. The antigen can be from a bacterial, viral or parasitic pathogen; and from the group consisting of an influenza virus, Herpes Simplex Virus (HSV) or a papilloma virus. A proviso explains that each of the truncated subunit coding regions has a 5' deletion and encodes a subunit peptide not having amino terminal bacterial signal peptide. A particle delivery device loaded with a particulate vaccine composition is also described. |
| priorityDate | 2000-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 950.