abstract |
A liquid propellant-free pharmaceutical preparation comprises a tiotropium salt as one active substance, in a concentration based on tiotropium of between 0.0005 and 5 % by weight, a second active substance selected from antiallergics, antihistamines, steroids and/or leukotriene antagonists, water or a water/ethanol mixture as solvent, in which at least the tiotropium salt is dissolved, an acid for achieving a pH between 2.0 and 3.1, a preservative, and optionally a complexing agent, stabilizer, cosolvent and/or other adjuvants and additives in addition to the preservative. The pharmaceutical preparation can be used as a medicament for the treatment of asthma and/or COPD for administration by inhalation. |