| abstract |
Spray drying process for the preparation of pharmaceutical compositions containing small particles of phospholipid-stabilized fenofibrate is disclosed. The spray dried powdered compositions prepared according to this process and the dosage forms of fenofibrate (capsules, tablets, powders, granules, and dispersions) prepared from these powdered compositions is also disclosed. These powdered compositions and dosage forms are useful in the treatment of dyslipidemia and dyslipoproteinemia and have the advantage that they provide reduced in vivo variability in the bioavailability of fenofibrate active species among fed and fasted patients when administered orally. |