| abstract |
New derivatives of cyano-aryl (or cyanoheteroaryl)-carbonyl-piperazinyl-pyrimidines, formula I (see below) are disclosed. R1 represents an OR3 radical, wherein R3 represents a radical deriving from a saturated hydrocarbon with a linear or branched chain of 1 to 4 carbon atoms and R2 represents a phenyl radical substituted at least by a cyano radical (-CN), or a radical of a 5 or 6-membered heteroaromatic ring substituted by at least one cyano radical (-CN). The physiologically acceptable salts of said derivatives can be used in human and/or veterinary therapeutic applications as sedatives, anticonvulsants, hypnotics and general anaesthetics. |