| abstract |
Vaccine formulations suitable for oral administration are described. The vaccine formulations are in a solid form comprising antigen and a suitable excipient, which after insertion into the mouth, rapidly dissolve in saliva. Specifically, the solid form may consist of a cake of vaccine which is formed from a liquid solution or suspension by sublimation. Preferred vaccines are those containing antigens which are derived from pathogens that normally infect or invade the host through a mucosal membrane, or those vaccines that further comprises an antacid. |