| abstract |
Indole, azaindole and indazole derivative compounds of the formula (Ib) which are useful for the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals are disclosed, wherein the variables shown in formula (Ib) are as defined in the specification. These compounds of formula (Ib) and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, which makes them suitable for use in the treatment of a number of disease states including cancer and rheumatoid arthritis. |