abstract |
A multi-valent immunogenic composition comprising a conjugate of a carrier protein and the capsular polysaccharide or oligosaccharide of H. influenzae type B at a dose of 1-5 micrograms of polysacchadde or oligosaccharide, with TT, DT or CRM197 as carrier protein, wherein said composition additionally comprises 2 or more further bacterial polysaccharides or oligosaccharides capable of conferring protection to a host against infection by the bacteria from which they are derived, and wherein the H. influenzae type B capsular polysaccharide or oligosaccharide conjugate and all the further polysaccharides or oligosaccharides are not adsorbed onto an aluminium adjuvant salt. |