| abstract |
A method for the preparation of an immunogenic complex which comprises mixing a charged organic carrier and a charged antigen, in which the organic carrier and antigen are electrostatically associated, and wherein the charged antigen comprises one or more polypeptides from a region of Hepatitis C Virus (HCV) selected from the group consisting of core, E1, E2, NS3 and NS3/4a or an immunogenic fragment thereof, or a fusion protein comprising a HCV polypeptide or immunogenic fragment thereof. Also described is a method for the preparation of a vaccine composition comprising as the active component the above immunogenic complex. (62) Divided out of 518999 |