http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-518752-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8be6a6c990669567cc455d32b00535e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-724 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-16 |
| filingDate | 2000-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cd66f074394b4394a5d1909ec8a04a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5523c76f13ad22bd5ad949bc50d1895 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9313d98186940edee8c3dbf06830747f |
| publicationDate | 2003-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-518752-A |
| titleOfInvention | 6-mercapto-cyclodextrin derivatives that are useful as reversal agents for drug-induced neuromuscular block |
| abstract | A 6-mercapto-cyclodextrin derivative of formula I, wherein: m is 0-7 and n is 1-8 and m+n = 7 or 8; R is (C1-6)alkylene, optionally substituted with 1-3 OH groups, or (CH2)o-phenylene-(CH2)p ; o and p are independently 0-4; X is COOH, CONHR1, NHCOR2, SO2OH, PO(OH)2, OCH2-CH2-O)q-H, OH or tetrazol-5-yl; R1 is H or (C1-3)alkyl; R2 is carboxyphenyl; q is 1-3; or pharmaceutically acceptable salts thereof; with the exclusion of 6-per-deoxy-6-per-(2-hydroxyethylthio)-â-cyclodextrin; 6-mono-deoxy-6-mono-(2-hydroxyethylthio)-â-cyclodextrin ; 6-per-deoxy-6-per-(2-hydroxyethylthio)-g-cyclodextrin; 6-per-deoxy-6-per-(carboxymethylthio)-â-cyclodextrin; 6-mono-deoxy-6-mono-(carboxymethylthio)-â-cyclodextrin; 6A,6B-dideoxy-6A,6B-bis [(o-carboxyphenyl)thio]-â- cyclodextrin; 6A,6B-dideoxy-6A,6B-bis (carboxymethylthiol)-â-cyclodextrin and 6-per-deoxy-6-per-(2, 3-dihydroxypropylthio)-â- cyclodextrin. These 6-mercapto-cyclodextrin derivatives are suitable for use in the reversal of drug-induced neuromuscular block caused by neuromuscular blocking agent (NMBA, also called a muscle relaxant). |
| priorityDate | 1999-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.