http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-518594-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2000-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed727abe3ebdc4eb8f6d043d012c7f42 |
| publicationDate | 2003-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-518594-A |
| titleOfInvention | Treatment of eye conditions related to high intraocular pressure with a cyclic guanosine 3',5'-monophosphate phosphodiesterase type 5 inhibitor |
| abstract | Use of cyclic guanosine 3',5'-monophosphate phosphodiesterase type 5 inhibitor of formula (I), a salt or solvate thereof for treating or preventing central retinal or posterior ciliary artery occlusion is disclosed, wherein: R1 is H, C1-C3 alkyl, C3-C5 cycloalkyl, or perfluoroalkyl; R2 is H, C1-C6 alkyl optionally substituted by OH, C1-C3 alkoxy, or C3-C6 cycloalkyl, or C1-C3 perfluoroalkyl; R3 is C1-C6 alkyl, C3-C6 alkenyl, C3-C6 alkynyl, C3-C7 cycloalkyl, C1-C6 perfluoroalkyl, or (C3-C6 cycloalkyl)C1-C6 alkyl; R4 taken together with the nitrogen atom to which it is attached completes a pyrrolidinyl, piperidino, morpholino, or 4-N-(R6)-piperazinyl group; R5 is H, C1-C4 alkyl, C1-C3 alkoxy, NR7R8, or CONR7R8; R6 is H, C1-C6 alkyl, (C1-C3 alkoxy)C2-C6 alkyl, hydroxy C2-C6 alkyl, (R7R8N)C2-C6 alkyl, (R7R8NCO) C1-C6 alkyl, CONR7R8, CSNR7R8, or C(NH)NR7R8; and R7 and R7R8 are each independently H, C1-C4 alkyl, (C1-C3 alkoxy)C2-C4 alkyl, or hydroxy C2-C4 alkyl. |
| priorityDate | 1999-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 192.