http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-518488-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90bdd3287688eb3c00e3b10a6877fb97 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-683 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2000-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2f0d05d7f13bd1eff7a4cc2fc5414ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b64c5f39877992531971c2e138914a33 |
| publicationDate | 2004-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-518488-A |
| titleOfInvention | Methods of identifying DNA fragments of genes that are Identical by descent for two or more individuals |
| abstract | Methods of identifying DNA fragments comprising DNA that is identical by descent for two individuals are disclosed. The methods comprise contacting a sample of genomic DNA from each of two individuals with a restriction endonuclease; methylating one of the DNA samples; mixing the methylated DNA sample and the unmethylated DNA sample, and incubating the DNA sample mixture under denaturing conditions; further incubating the DNA sample mixture under conditions which allow re-annealing of the DNA samples to form a mixture comprising homohybrid DNA fragments and heterohybrid DNA fragments; contacting the mixture with restriction endonuclease(s) which digest homohybrid DNA fragments; contacting the mixture with an endonuclease(s) which cleaves both strands of a mismatch-containing heterohybrid DNA fragment, to form a DNA sample mixture comprising perfectly-matched heterohybrid DNA fragments which are enriched in DNA fragments that are identical by descent for the two individuals |
| priorityDate | 1999-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.