| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e7acced496b5ded1fe725568c662fa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-128
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-124
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0032 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate |
2000-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7b415411149973757e8851be6d318ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8919788516ef36d861c41d27284fa7b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6664690596e173e2795787f5c3056711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b19f357797f3e9238b2caf08df06f80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eef9258233a09dd8d9c97da51d0b338a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3ecf195432af701477260a60f100adc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a483b9eef502d27fcd98530708383cf8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d039b02be7bec966d5b48fb8ae0199f |
| publicationDate |
2004-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-517017-A |
| titleOfInvention |
Targeting multimeric imaging agents through multiocus binding and improving the efficacy of in vivo contrast agents |
| abstract |
Multimeric contrast agent compounds which exhibit improved relaxivity properties upon binding to endogenous proteins or other physiologically relevant sites for diagnostic imaging are disclosed. These compounds consist of: a) two or more Image Enhancing Moieties (IEMs) (or signal-generating moiety) comprising multiple subunits; b) two or more Target Binding Moieties (TBMs), providing for in vivo localization and multimer rigidification; c) a scaffold framework for attachment of the above moieties; and d) optional linkers for attachment of the IEMs to scaffold. Pharmaceutical compositions comprising these compounds and methods of using the compounds and compositions for contrast enhancement of diagnostic imaging are also disclosed. |
| priorityDate |
1999-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |