| abstract |
Compounds of formula (I), wherein: A is -Ca"C-, -CH=CH-, or -CH2-CH2-, n is equal to 1 or 2, X is hydrogen, chlorine, fluorine, methyl, or methoxy, Y is hydrogen, chlorine or fluorine, R1 is cyclohexyl optionally substituted with methyl, phenyl, cycloheptyl, butyl, dicyclopropylmethyl, bicyclo[3.2.1]octanyl, tetrahydropyranyl, tetrahydrothiopyranyl, or adamantly, or R1 is phenyl, and R2 and R3 form a 5-8 membered amine ring, morpholinyl, or a phenyl-tetrahydropyridal. The compounds are used in the manufacture of medicaments for treating the positive and negative symptoms of schizophrenia. |