| abstract |
A method of therapeutic management of infertility by programming of controlled ovarian stimulation (COS) and assisted reproductive procedures (ART) comprising the steps of a) suppression of premature ovulation with an LHRH-antagonist in COS and ART with multiple follicle and oocyte development; b) programming the start of COS by the administration of progestogen only - or alternatively combined oral contraceptive preparations; c) exogenous stimulation of the ovarian follicle growth by subcutaneous or intramuscular administration of I) a gonadotrophin or by ii) oral ingestion of clomiphene followed by gonadotrophin application; d) ovulation induction with HCG, native LHRH, LHRH-agonist or recombinant LH; e) application of assisted reproduction techniques, especially IVF, ICSI, GIFT, ZIFT or by intrauterine insemination by sperm injection. |