http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-514383-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afc5d8c9ee6673323cee3e2d19bc5146 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-55 |
| filingDate | 2000-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f664a0b50aab200d45bc5bbc9d9463cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9afcda6a0f8a58dec2d4b07d5f381c9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6b65f0804eaf181634b426a4d14c880 |
| publicationDate | 2004-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-514383-A |
| titleOfInvention | Process of preparing 3S-3-amino-3-aryl propionic acid and derivatives thereof |
| abstract | A process for preparing a compound of formula (I) comprising reacting a compound of formula (II), at a pH range of between about 7 and about 11, to form a compound of formula (III) wherein R5 is N-t-butoxycarbonyl, reacting a compound of formula (III) with at least 0.5 equivalents of (lR, 2S)- (-) ephedrine, in an alkyl acetate solvent, to form a salt of formula (IV) wherein Ph is phenyl, reacting the salt of formula (IV) with an inorganic base in water to form a carboxylate salt of the compound of formula (V), acidifying the carboxylate salt of the compound of formula (V) with an acid of pKa less than or equal to three, to a pH of between about 3.5 and about 6.5, to form the compound of formula (V), reacting the compound of formula (V), at a temperature less than about25 C, to form the compound of formula (I). |
| priorityDate | 1999-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.