| abstract |
A pharmaceutical composition comprising zolpidem consisting of a controlled release dosage form adapted to release zolpidem over a predetermined time period according to a biphasic in vitro dissolution profile where the first phase is an immediate release phase having a maximum duration of 20 minutes and the second phase is a prolonged release phase, and wherein 40% to 70% of the total amount of zolpidem is released during the immediate release phase, and the time for release of about 90% of the zolpidem is between 2 and 6 hours. |