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filingDate 1999-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2adcd8a6fc1d7ab911a766274c26c124
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publicationDate 2003-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-510231-A
titleOfInvention Omeprazole formulation comprising an alkaline core and an enteric coating
abstract A stable pharmaceutical dosage formulation for oral administration consisting essentially of: (a) a core comprising 5-50 weight percent based on the total weight of the core of omeprazole, a surface active agent, a filler , a binder, 0.5-10 weight percent based on the total weight of the core of a pharmaceutically acceptable alkaline agent, wherein the alkaline agent is selected from the group consisting of lysine and arginine; and (b) a coating layer surrounding the core that comprises an enteric coating agent, 5-50 weight percent based on the total weight of the coating layer of an inert processing aid and optionally a plasticizer wherein the enteric coating layer is applied directly to the omeprazole containing core without a separating layer between the omeprazole containing core and enteric coating layer.
priorityDate 1998-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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