| abstract |
An amide derivative or a pharmaceutically-acceptable salt or in-vivo-cleavable ester thereof has the formula I wherein: R3 is or halogen; m is 0, 1, 2 or 3; p is 0 to 2 Q is optionally substituted heteroaryl, heteroaryloxy, heteroarylalkoxy, heteroarylamino, N-alkyl heteroarylamino, heteroarylalkylamino, N-alkyl heteroarylalkylamino, heteroarylcarbonylamino, heteroarylsulphonylamino, heteroarylsulphamoyl or heteroarylalkanoylamino and R1 and R2 are as defined in the specification. The compounds are useful to treat medical conditions mediated by cytokines |