| abstract |
Use of a tetracycline or its derivative as a pharmaceutical for use in enhancing interleukin-10 production in mammalian cells or tissues. The derivative may include 4-dedimethylaminotetracycline, 6-demethyl-6-deoxy-4-dedimethylaminotetracycline, tetracycline-pyrazole, 7-chloro-4-dedimethylaminotetracycline, 4-hydroxy-4-dedimethylaminotetracycline, 12-alpha-dexoy-4-dedimethylaminotetracycline, 5-hydoxy-6-alpha-dexy-4dedimethylaminotetracycline, 4-dedimethylamino-12-alpha-dexyanhydrotetracycline, 7-dimethylamino-6-demethyl-6deoxy-4-dedimethylaminotetracycline, tetracyclinonitrile, anti-microbial tetracycline, minocycline and doxycycline. |