| abstract |
A compound of formula (1) or a pharmaceutically acceptable derivative thereof wherein: R1 is hydrogen or optionally substituted aryl, alkyl, alkenyl, adamantly, cycloalkyl, cycloalkenyl or -C(R11)(R12)(R13); X is hydrogen, cyano, alkyloxy, dimethoxymethyl or =O and Y is hydrogen or optionally substituted alkyl, alkenyl, benzyl or cycloalkyl group or X and Y together with the atoms to which they are attached form a 5- to 7-membered optionally substituted optionally saturated heterocyclic ring. A pharmaceutical composition thereof is useful to promote repair of neuronal damage caused by disease and physical trauma. |