abstract |
A compound of formula (I), wherein: Y represents a carbon atom, Z is CH linked to Y via double bond and X is methylene or NR11, or Z is methylene and X is a carbon atom linked to Y via a double bond, A is an optionally substituted C1-2alkylene chain, R is halogen or C1-4alkyl, R1 is hydrogen, halogen or C1-4alkyl, and R2 is an optionally substituted phenyl, or a 5-membered heteroaryl group. The compounds are used in the manufacture of medicaments for use as NMDA receptor antagonists. |