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filingDate 2000-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddbe392a7dff95a847c466ded39e9a04
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publicationDate 2001-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-508390-A
titleOfInvention New dihydrofuro[3,4-b]quinolin-1-one compounds, cyclopenta[b]-quinolinone compounds, thieno[3,4-b]quinolinone compounds, and acridinone compounds; a process for their preparation and pharmaceutical compositions containing them
abstract There is disclosed: a compound of formula (I), a method of preparation for this compound and pharmaceutical compositions thereof, wherein: ---- represents a single bond or no bond R0 represents H, hydroxy group, or a linear or branched (C1-C6) alkoxy group; R1 and R2, which are identical or different, each represents: hydrogen, halogen, linear or branched (C1-C6) alkyl group, linear or branched (C1-C6) alkoxy group, hydroxy group, linear or branched (C1-C6) polyhaloalkyl group, nitro group, amino group optionally substituted by one or two linear or branched (C1-C6) alkyl groups, group of formula (II) wherein m represents an integer from 1 to 4, or R1 and R2 form together with the carbon atoms carrying them an aromatic or non-aromatic mono- or bi-cyclic group having from 5-12 ring members and optionally containing 1 or 2 heteroatoms selected from O, S and N; R3 represents H or a group of formula R4 wherein R4 represents: - an aryl group, - a heteroaryl group, - a (C3-C8) cycloalkyl group, - a linear or branched (C1-C6) alkyl group optionally substituted by an aryl group, by a heteroaryl group, by a hydroxy group, by a linear or branched (C1-C6) alkoxy group, or by a group of formula NR5R6 wherein R5 and R6 (which are identical or different) each represents a linear or branched (C1-C6) alkyl group or a linear or branched (C1-C6) hydroxyalkyl group, or R5 and R6 form together with the nitrogen atom carrying them a nitrogen heterocycle,- a group of formula COR7, wherein R7 represents one of the following groups: o aryl, o linear or branched (C1-C6) alkyl (optionally substituted by a group of formula NR8R9 wherein R8 and R9, which are identical or different, each represents a linear or branched (C1-C6) alkyl group or a linear or branched (C1-C6) hydroxyalkyl group, or form together with the nitrogen atom carrying them a nitrogen heterocycle), o amino optionally substituted by one or more groups aryl, heteroaryl or linear or branched (C1-C6) alkyl (optionally substituted by a group of formula NR8R9), o OR10 wherein R10 represents H or an aryl group or linear or branched (C1-C6) alkyl (optionally substituted by a group of formula NR8R9), X represents O or S or a -CH2 - or -CH2-CH2- group; Ar represent an aryl, heteroaryl or aryl-(C1-C6) alkyl group in which alkyl is linear or branched; wherein aryl is phenyl, biphenyl, naphthyl or tetrahydronaphthyl (each of those groups being optionally substituted as defined in the specification), heteroaryl is an aromatic mono- or bi-cyclic group having from 5-12 ring members and containing 1-3 heteroatoms selected from O, S and N (each of these heteroaryl groups being optionally substituted as defined in the specification), and nitrogen heterocycle is a saturated monocyclic group having from 5-7 ring members and containing 1-3 heteroatoms selected from O, S, and N, where one of the heteroatoms of the nitrogen heterocycle must be N; their optical isomers, hydrates, solvates and pharmaceutically acceptable addition salts thereof.
priorityDate 1999-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 64.