http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-508248-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c275038cf36535d44a526cb28203c03d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22 |
| filingDate | 2000-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61244674fbd634e1a8342feb6580b7b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00d36a05b6204d15f01ee3bc478c7b6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22cd448cc00fe2412e1ac70499c0ca3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19949fd3ed6326cc004add4cc8d0df1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3bdf4407ba01488e94ce7eb430ffc1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba634a5f110a11c04ce2604717933cfd |
| publicationDate | 2001-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-508248-A |
| titleOfInvention | Camptothecin analogue compounds and pharmaceutical use |
| abstract | In the compounds of formula (I): n is 0, 1 or 2 R1, R2, R3, R4 and R5 are selected from H, halogen, alkyl, alkenyl, alkynyl, perhaloalkyl, C3-C11 cycloalkyl, C3-C11 cycloalkyl-alkyl, hydroxy, hydroxyalkyl, alkoxy, alkoxyalkyl, alkoxycarbonyl, acyloxy, carboxy, nitro, cyano, aminocarbonyl, (CH2)pNRaRb and OC(O)NRaRb, wherein p is 0 to 6, Ra and Rb are H, alkyl, C3-C11cycloalkyl, C3-C11 cycloalkyl-alkyl, acyl, optionally substituted aryl or arylalkyl group, or Ra and Rb form together with the nitrogen atom carrying them a pyrrolyl, piperidinyl or piperazinyl group, wherein each of those cyclic groups may be optionally substituted; or Two adjacent groups R2, R3, R4 and R5 form together with the carbon atoms carrying them, a group O(CH2)tO, wherein t is 1-3; R60, R70n, R80 and R90 are selected form H, hydroxy, alkoxy, O-(CO)-X or O(CO)NXW, wherein X and W are alkyl, alkenyl, alkynyl, C3-C11 cycloalkyl, C3-C11 cycloalkyl-alkyl or an optionally substituted aryl or arylalkyl group; R61, R71n, R81 and R91 is H, alkyl, alkenyl or alkynyl, or taken in pairs on adjacent carbon atoms, together form a bond or an oxirane group, or two geminal groups (R60 and R61) and/or (R70 and R71) and/or (R80 and R81) and/or (R90 and R91) together form an oxo group or a group O(CH2)t1O, wherein t1 is 1 to 3. The compounds may be used in pharmaceuticals for the treatment of cancerous diseases. |
| priorityDate | 1999-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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