| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e1167a7b2309b8d29d882a38e9bc76de |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0081 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate |
1999-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99bae89e4bb668eac0c4d90b9618fede
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec8892b088ae2efe9f5b82a0e286c014 |
| publicationDate |
2003-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
NZ-508242-A |
| titleOfInvention |
Efficient ex vivo expansion of CD4+ and CD8+ T-Cells from HIV infected subjects |
| abstract |
Described is a method of obtaining an expanded population of target T cells with reduced levels of HIV from an initial population of T cells obtained from an appropriate subject infected with HIV. The method comprises: (1) preparing a CM containing a combination of factors effective for promoting the expansion of the chosen target T cells by incubation of a starting population of blood cells in a growth medium containing at least two plant-derived mitogens; and (2) culturing an initial population of T cells containing the target T cells in the presence of an effective amount of the CM from step (1), to expand the population of target T cells in the culture while maintaining reduced virus levels. |
| priorityDate |
1998-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |