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filingDate 1999-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_391727bbf07af1dd434eaccc99b0edc0
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publicationDate 2003-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-506532-A
titleOfInvention Composition comprising a process of forming dried core particle topiramate coated with a taste masking substance followed by a binder further coated with a further taste masking substance and method for treating epilepsy and convulsions
abstract A pharmaceutical composition can be formed by preparing core particles comprising the active agent topiramate, drying the particles to form dried core particles and then coating the dried particles with a taste masking mixture to form coated particles. The coated particles are then dried to form the composition. The amount of the taste masking agent ranges from about 7% to about 15% by weight of the pharmaceutical composition. Also described is a pharmaceutical composition comprising core particles having an initial particle size of between 0.1 mm and 2.5 mm and a taste masking coating that comprises about 7% to about 15% by weight of the composition. The composition can comprise 85 to 93% by weight core beads and 7 to 15% by weight of coating. The core beads comprise 18 to 21% by weight of topiramate and 8-11% by weight of povidone and 58 to 61% by weight of sugar. The coating comprises 6-9% by weight of cellulose acetate and 2 to 5% by weight of povidone. The compositions can be used for treating convulsion or epilepsy.
priorityDate 1998-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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