Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afc5d8c9ee6673323cee3e2d19bc5146 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-58 |
filingDate |
1999-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_391727bbf07af1dd434eaccc99b0edc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2d7b59cb298101b4b1e82476289f66f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ffc7657b3c1940002df197741e13ff1 |
publicationDate |
2003-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
NZ-506532-A |
titleOfInvention |
Composition comprising a process of forming dried core particle topiramate coated with a taste masking substance followed by a binder further coated with a further taste masking substance and method for treating epilepsy and convulsions |
abstract |
A pharmaceutical composition can be formed by preparing core particles comprising the active agent topiramate, drying the particles to form dried core particles and then coating the dried particles with a taste masking mixture to form coated particles. The coated particles are then dried to form the composition. The amount of the taste masking agent ranges from about 7% to about 15% by weight of the pharmaceutical composition. Also described is a pharmaceutical composition comprising core particles having an initial particle size of between 0.1 mm and 2.5 mm and a taste masking coating that comprises about 7% to about 15% by weight of the composition. The composition can comprise 85 to 93% by weight core beads and 7 to 15% by weight of coating. The core beads comprise 18 to 21% by weight of topiramate and 8-11% by weight of povidone and 58 to 61% by weight of sugar. The coating comprises 6-9% by weight of cellulose acetate and 2 to 5% by weight of povidone. The compositions can be used for treating convulsion or epilepsy. |
priorityDate |
1998-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |