abstract |
The compound of formula II is useful in preparing a medicament for the treatment of a neoplasia. R4 is lower haloalkyl, R5 is hydrido and R6 is phenyl optionally substituted with radicals selected from the group consisting of halo, lower alkylthio, lower alkylsulfonyl, cyano, nitro, lower haloalkyl, lower alkyl, hydroxyl, lower alkenyl, lower hydroxyalkyl, carboxyl, lower cycloalkyl, lower alkylamino, lower dialkylamino, lower alkoxycarbonyl, aminocarbonyl, lower alkoxy, lower haloalkoxy, sulfamyl, five or six membered heterocyclic and amino. |