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filingDate 1998-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbd7c5642c47bff82bff2e229466d394
publicationDate 2002-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-504884-A
titleOfInvention Synthesis of the dihydroindole C-ring of CC-1065/duocarmycin analogs and certain intermediates
abstract The dihydroindole C-ring found in CC-1065/duocarmycin analogs is formed by the 5-(exo-trig) radical cyclization of an aryl halide onto a tethered vinyl chloride forming with chlorine installed as a suitable leaving group for subsequent cyclopropane spirocyclization. Also disclosed are various compounds of formula as depicted.
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