http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-504420-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0264ab149dd139d522f7f14b1a3ea9e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 |
| filingDate | 1998-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8fd06a834cfdbd8afe443024cd70e8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e52fa114065f342ff60e970f382ddfbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7240188cdd84ac68f458668dde001f5 |
| publicationDate | 2003-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-504420-A |
| titleOfInvention | Combination of tetrahydropyridins and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementia |
| abstract | A pharmaceutical composition comprising: (a) a compound selected from 1-(2-napht-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridin and a compound (I) wherein: Y is -CH- or -N-; R1 is hydrogen, halogen, hydroxyl, CF3, alkyl or alkoxyl group; R2 is hydrogen, halogen, hydroxyl, CF3, alkyl or alkoxyl group; R3 and R4 each represent hydrogen or alkyl; X is: (i) alkyl; alkoxyl; carboxyalkyl; alkoxycarbonyl alkyl; carboxyalkoxyl; or alkoxycarbonyl alkoxyl; (ii) a radical selected from cycloalkyl, cycloalkyloxy, cycloalkylmethyl, cycloalkylamino and cyclohexenyl; said radical being optionally substituted by halogen, hydroxy, alkoxy, carboxy, alkoxycarbonyl, amino, mono- or di-alkyamino; or (iii) a group selected from phenyl, phenoxy, phenylamino, N-alkyl-phenyl-amino, phenylmethyl, phenylethyl, phenylcarbonyl, phenylthio, phenylsulphonyl, phenylsulphinyl or styryl; said group capable of being mono- or polysubstituted on the phenyl group by halogen, CF3, alkyl, alkoxy, cyano, amino, mono- or di-alkylamino, acylamino, carboxy, alkoxycarbonyl, aminocarbonyl, mono- or di-alkylaminocarbonyl, amino alkyl, hydroxy alkyl, or halogeno alkyl; (b) a compound active in the symptomatic treatment of DAT, provided that when constituent (a) is other than 1-(2naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridin, the constituent (b) is an acetylcholinesterase inhibiting agent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8481565-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8507527-B2 |
| priorityDate | 1997-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.