http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-503415-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86d5ed9cdf8be19c83262f867b7531b9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H10K85-344 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L51-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L51-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 |
| filingDate | 1998-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6aa55dfd8934680817bc3eb034136049 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05b5bd3d0d1e615079765db960e73d50 |
| publicationDate | 2001-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-503415-A |
| titleOfInvention | Binuclear transition metal complex and its use as a photoinduced nucleic acid cleavage agent, or its use for treating cancer, tumours or infections |
| abstract | The binuclear DNA-threading transition metal complex has the general formula: (L1)-M1-(D1-B-D2)-M2-(L2) wherein: D1-B-D2 is a bridging ligand; D1 is a polycyclic heteroaromatic ligand with at least four rings, in which aza nitrogens can form a bidentate or tridentate chelate with M1; D2, identical with or different from D1, is any bi- or oligodentate ligand co-ordinated to the transition metal M2; B, covalently linking the ring system D1 to D2, is any appropriately substituted chain of at least two atoms; M1 is a transition metal ion with octahedral co-ordination sphere that is capable of forming substitution-inert co-ordination bonds to the D1 moiety of the bridging ligand as well as to at least one of the bi- or polydentate ligands of set L1; M2 is any transition metal ion; L1 comprise a set of 1-3 ancillary ligands that saturate the remaining co-ordination sphere of M1, at least one of these ligands forming substitution-inert co-ordination bonds to M1 in a bi-, tri- or tetradentate chelate; L2 comprises a set of 1-4 ancillary ligands that saturate the remaining co-ordination sphere of M2. Also described are pharmaceutical compositions (especially cytostatic compositions and antibiotics) comprising the complex described above. The complexes described above are used as photo-induced nucleic acid cleavage agents; or used for treating cancer, tumours, or infection. |
| priorityDate | 1997-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.