abstract |
Described is a pharmaceutical composition and process for preparing swallowable methylcellulose tablets that disintegrate rapidly and meet USP standards in 0.1 N hydrochloric acid as well as water. The tablet comprises a compacted mixture of methylcellulose having a viscosity of >1000 centipoise, and an edible calcium salt selected from the group consisting of dibasic calcium phosphate dihydrate, calcium phosphate anhydrous, and tribasic calcium phosphate; or mixtures thereof. The preferred edible calcium salt is the dibasic calcium phosphate dihydrate salt, as it provides good compressibility. |