| abstract |
A compound of the Formula (I), a N-oxide form, a pharmaceutically acceptable acid addition salt or a stereo-chemically isomeric form thereof, wherein n is zero, 1, 2 or 3; X is N or CH; each R1 independently is halo, nitro, cyano, amino, hydroxy, C1-4alkyl, C1-4alkyloxy or trifluoromethyl; R2 is hydrogen; C3-7alkenyl; C3-7alkynyl, aryl; C3-7cycloalkyl; C1-6alkyl or C1-6alkyl substituted with hydroxy, C1-4alkyloxy, C3-7cycloalkyl or aryl; R3 and R4 each independently is hydrogen, C1-6alkyl, C3-7cycloalkyl or aryl; or R3 and R4 taken together form a bivalent radical -R3-R4- of formula (a)-(e), wherein; R5a, R5b, R5c, R5d each independently are hydrogen, C1-6alkyl or aryl; and aryl is phenyl or phenyl substituted with one, two or three substituents selected from halo, nitro, cyano, amino, hydroxy, C1-4alkyl, C1-4alkyloxy or trifluoromethyl. The aryl group is optionally substituted phenyl; as anti-fungals; their preparation, compositions containing them and their use as a medicine. |