http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-501709-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_938a6d7a15cbc93a74abe1953eb25d47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
| filingDate | 1996-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a859122e948a7a75cf6b7f727ec814d |
| publicationDate | 2000-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-501709-A |
| titleOfInvention | Pharmaceutical compositions comprising a compound having affinity for FKB12, a neurotrophic factor and a pharmaceuticl carrier |
| abstract | The application relates to methods and pharmaceutical compositions for stimulating the growth of neurites in nerve cells. The compositions comprise a neurotrophic amount of a compound of the formula below, where A is O, NH or Nalkyl; T is heteroaryl, aryl or substituted cyclohexyl, E is O, CH-U. J is H or alkyl, K is alkyl, benzyl or cyclohexylmethyl, or J and K together form a 7 membered heterocyclic ring and B, D and U are as defined in the specification. which binds to the FK-506 binding protein (FKBP) and a neurotrophic factor, such as nerve growth factor NGF. The methods comprise treating nerve cells with the above-described compositions or compositions comprising the FKBP binding compound without a neurotrophic factor. The methods can be used to promote repair of neuronal damage caused by disease or physical trauma. |
| priorityDate | 1995-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.