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filingDate 1998-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d562f4fe78e003e0b247d03e70650c48
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publicationDate 2000-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-337589-A
titleOfInvention [1,4]diazepino[6,7,1-hi]indol-4-ones and there use in treating inflammatory diseases
abstract The specification describes compounds that inhibit phosphodiesterase 4 having Formula (I) wherein Z is CH, then Z1 and Z2 both are CH or N; or when Z is N then Z1 and Z2 are CH and X1 and X2 are as depicted in figure 2. The compounds are reported to prevent or treat asthma, atopic dermatitis, rheumatoid arthritis, inflammatory bowel disorders, pulmonary hypertension, liver injury, bone loss, septic shock, or multiple sclerosis.
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