http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-336460-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c275038cf36535d44a526cb28203c03d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 1999-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4843d73987d4f6c903298b24244145ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2468b558a58ade86749e0918af5d48b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a7b7ce66caacfc962af6e73ebac65f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a78b41c51394a16a41705e3c819e90c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_019a40b9528c8d0267e70b67b1162ba7 |
| publicationDate | 2000-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-336460-A |
| titleOfInvention | Antioxidant nitrone compounds for neurodegenerative disorders |
| abstract | Nitrone compounds shown as Formula (I) are described, as well as their preparation and pharmaceutical compositions containing them. These compounds are antioxidants, traps for reactive oxygenated species, which are capable of combating "oxidation stress" in the cerebral region. The compounds are capable of combating cognitive disorders associated with cerebral aging or neurodegenerative disorders, and also combating neurone death associated not only with acute neurodegenerative disorders such as, for example, ischaemia and epilepsy, but also with progressive neurodegenerative disorders, such as, for example Alzheimer's disease, Pick's disease or neurodegeneracies of the basal ganglia. Nitrone compounds as described by Formula (I); Wherein: W represents an aryl group, aryl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched, a heteroaryl group or a heteroaryl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched, R1 represents a linear or branched (C1-C6)alkyl, a linear or branched (C2-C6)alkenyl group, a linear or branched (C2-C6)alkynyl group, an aryl group, a cycloalkyl group, an aryl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched, or a cycloalkyl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched, R2 represents a H atom, a linear or branched (C1-C6)alkyl group, an aryl group, an aryl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched, a cycloalkyl group, a cycloalkyl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched, a heterocycloalkyl group, a heterocycloalkyl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched, a heteroaryl group, a heteroaryl-(C1-C6)alkyl group in which the alkyl moiety may be linear or branched, a linear or branched (C1-C6)acyl group, a linear or branched (C1-C6)alkylsulphonyl group in which the alkyl moiety may be linear or branched, or a linear or branched (C2-C6)alkenyl group, Their isomers, and also additions salt thereof with a pharmaceutical acceptable acid or base. |
| priorityDate | 1998-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.