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publicationDate 2000-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber NZ-333721-A
titleOfInvention Pharmaceutically acceptable synthetic polysaccharides
abstract A synthetic polysaccharide that includes an antithrombin III binding domain and possesses the anticoagulant and antithrombitic pharmaceutical activities of heparin. The polysaccharide consists of a concatenation of five monosaccharides supporting a total of two carboxylic acid groups and at least four sulpho groups. The antithrombin III binding domain is directly bound at the non-reducing end by a thrombin binding domain that includes a concatenation of 10-25 monosaccharide units selected from hexoses, pentoses or deoxy sugars of which all the hydroxyl groups are etherified by a C1-6 alkyl group or esterified in the form of sulpho groups.
priorityDate 1996-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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