| abstract |
Compounds of the formula depicted above may be used for preventing or treating respiratory, ocular, and/or gastrointestinal disorders, particularly nasal congestion, glaucoma, diarrhea and asthma. In the formula above: (a) R is unsubstituted C1-C3 alkanyl or alkenyl; (b) R' is selected from unsubstituted C1-C3 alkanyl or alkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thiol; and halo; and (c) R'' is selected from hydrogen; unsubstituted C1-C3 alkanyl or alkenyl; methyl monosubstituted with hydroxy, thiol or amino; unsubstituted C1-C3 alkylthio or alkoxy; amino; halo; unsubstituted amide; unsubstituted or C1-C3 alkanyl or alkenyl substituted amido; unsubstituted sulfoxide; unsubstituted sulfonyl; and cyano. |