| abstract |
Compounds of the formula (I) or salts thereof are claimed wherein: A is a heterocyclic of 5-7 ring atoms wherein 1-3 heteroatoms from the group O, N or S are present; R1 is H or F; R2 is alkyl, alkoxy or oxo and p is 0 to 2; Z is carbon or nitrogen and the dotted line is a single bond when Z is nitrogen and a single or double bond when Z is carbon; R3 and R4 are independently H or alkyl; n is 1 or 2; R5 is 2-, 3- or 4- pyridyl substituted in the meta position with respect to the methylene bridge with a group Y and optionally substituted (R6)q; Y is an optionally substituted phenyl, furanyl or thienyl; R6 is halogen, OH, alkoxy or alkyl and q is 0 to 3. A process for preparing the above compounds is claimed. A pharmaceutical composition containing the above compounds useful in treating CNS disorders is also claimed. |