http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-331458-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cfd95163539ad5d5bb1e5522a4755a29 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-26 |
| filingDate | 1996-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8dbe545c49d46f5383b0f2ab912e121 |
| publicationDate | 2001-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | NZ-331458-A |
| titleOfInvention | Use of 7-Adamantyl-naphth-2-yl(hetero)aryl carboxylic acids, derivatives thereof (retinoid analogues) in preparing medicaments; compounds having a polyether radical bound to a moiety of at least two carbon atoms in position-beta |
| abstract | A retinoid analogue or a salt thereof or its chiral analogues has the formula (I) wherein: R1 is methyl, CH2OH, -OR3 or -CO-R4; Ar is a radical of formula (a) to (d); R2 is a polyether radical having carbon in the position a to the carbon which is in the 6th position of the naphthyl radical; R3 is H, alkyl or -(CH2)m(CO)n-R8; R4 is H, alkyl, -N(R')(R"), or -OR9; R5 is H or halogen, alkyl, hydroxy, -OR9 or -OCOOR10; R8 is alkyl or a saturated heterocycle; R9 is H, alkyl, alkenyl, mono- or polyhydroxyalkyl, optionally substituted aryl or aralkyl or a sugar residue, amino acid or peptide residue; R10 is alkyl; R' and R" are independently H, alkyl, mono- or polyhydroxyalkyl, optionally substituted aryl, or a sugar residue, amino acid or peptide residue or together can form a saturated heterocycle and m is 1 to 3. The compound is useful in treating disorders and/or aliments related to an over-regulation of RAR receptors and/or a hypervitaminosis A. |
| priorityDate | 1995-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 388.