http://rdf.ncbi.nlm.nih.gov/pubchem/patent/NZ-326429-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95a22228273850f2f751eb644cc32a91 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13043 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
filingDate | 1997-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59e70396c7b589ea5d6402722a7aa620 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_267835a26e4f9fc6f800ee976e21e7d4 |
publicationDate | 2001-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | NZ-326429-A |
titleOfInvention | A producer cell containing a DNA sequence lacks functional env and functional gag-pol genes capable of producing a retroviral vector containing neither and its use in gene therapy |
abstract | A producer cell capable of producing a replication defective retroviral vector in an infective retroviral vector particle comprises: a) a first DNA sequence encoding the replication defective retroviral vector comprising: (i) a defective retroviral genome lacking functional env and functional gag-pol genes but having the remaining components essential for retroviral function and (ii) at least one heterologous gene and b) a set of DNA sequences encoding packaging components env and gag-pol wherein the DNA sequence encoding env is present on a separate construct to the DNA sequence encoding gag-pol; which producer cell is a fresh cell from a subject and is capable of delivering the heterologous gene to a target cell within a subject by in vivo production of the replication defective vector particles. |
priorityDate | 1996-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 454.