abstract |
Sulfates of 3 alpha, 7 beta-dihydroxy-5 beta-cholan-24-oic acid (UDCA) for use in the treatment of liver disease, inflammatory conditions of the gastrointestinal tract, colon and rectum cancer, a neoplasm of the colon or rectum and combinations thereof. Whereas UDCA is mainly transformed in the liver by conjugation, sulfates of UDCA can be advantageously and effectively delivered to the colon and other portions of the gastrointestinal tract. |